Medications for Hair Restoration in Southlake

And Surrounding DFW Areas

At Medrein Health & Aesthetics in Southlake, TX, we offer Medications, to help men and women address hair loss and promote hair regrowth and prevent hair loss.

What are the Medications for Hair Growth?

Medications for hair growth are topical or oral treatments designed to slow hair loss, stimulate hair follicles, and promote regrowth in individuals experiencing thinning or baldness due to genetics, hormonal changes, or medical conditions. Common options include:

  • Minoxidil (Rogaine): It’s used to stimulate hair growth and slow down hair loss, particularly in cases of hereditary hair loss (androgenic alopecia) in both men and women.

     

  • Spironolactone: This oral medication is sometimes prescribed off-label for women with hair loss.
  • DHT Inhibitors: DHT inhibitors, like finasteride, work by blocking the enzyme 5-alpha reductase, which converts testosterone into dihydrotestosterone (DHT), a hormone that contributes to hair loss. By reducing DHT levels, these inhibitors help to slow down or even reverse hair loss and promote hair regrowth. 

    • Finasteride (Propecia): This oral medication is available by prescription. It works by blocking the production of a hormone that contributes to hair loss.
    • Dutasteride (Avodart): This oral medication is also available by prescription. It works similarly to finasteride but may be more effective for some individuals.
  • Latanoprost: A prostaglandin analog originally used to treat glaucoma, has shown potential in promoting hair growth by extending the anagen (growth) phase of hair follicles. Its effectiveness has been particularly noted in enhancing eyelash and eyebrow density, with ongoing research exploring its broader applications for scalp hair restoration.

Minoxidil (Rogaine)

Minoxidil stimulates hair growth by opening potassium channels, which increases blood flow to hair follicles. This process is thought to promote hair growth by prolonging the anagen phase of the hair cycle. 

Mechanism of action:

  • Potassium channels
    Minoxidil opens potassium channels in vascular smooth muscles and hair follicles. This hyperpolarizes cell membranes, which increases blood flow around hair follicles. 

  • Blood flow
    Increased blood flow delivers oxygen and nutrients to hair follicles, which helps revitalize them and promote hair regrowth. 

  • Hair follicle size
    Minoxidil may also increase hair follicle size. 

  • Androgen effects
    Minoxidil may counteract the effects of androgens, such as dihydrotestosterone (DHT), which shrink hair follicles. 

Other effects 

  • Minoxidil may also stimulate cell proliferation, inhibit collagen synthesis, and stimulate vascular endothelial growth factor and prostaglandin synthesis.

 

How it’s used

  • Minoxidil is applied topically, or taken orally once or twice daily. It can take about 8 weeks to see initial results, and 4 months to see maximum effects. 

 

Side effects

  • Side effects of minoxidil include irritant and allergic contact dermatitis on the scalp. 
  • Can cause hair growth in other parts of the body.

Spironolactone

Both oral and topical Spironolactone can promote hair growth in men and women at dosages typically between 50-200mg per day (or even lower). The choice between oral and topical Spironolactone for hair growth depends on each person’s needs, preferences, and tolerance for potential side effects.

Mechanism of action: 

It appears to act at two sites: it blocks androgens at the hair follicle/sebaceous gland and it reduces the secretion of androgens from the adrenal gland. To check the effectiveness of this therapy, the hair growth and/or acne are assessed at 2 to 4 month intervals.

DHT Blockers

  • DHT and Hair Loss:
    DHT, a potent androgen, binds to androgen receptors in hair follicles, causing them to shrink and eventually stop producing hair, leading to hair loss. 
     
  • The Role of 5-Alpha Reductase:
    The enzyme 5-alpha reductase is responsible for converting testosterone into DHT. 
     
  • How DHT Blockers Work:
    DHT blockers, like finasteride and dutasteride, inhibit the activity of 5-alpha reductase, thereby reducing the amount of DHT produced and available to bind to hair follicle receptors. 
     
  • Mechanism of Action:
    • Inhibition of 5-Alpha Reductase: DHT blockers specifically target and inhibit the enzyme 5-alpha reductase, preventing the conversion of testosterone to DHT. 
       
    • Reduced DHT Levels: By inhibiting 5-alpha reductase, DHT blockers lower the levels of DHT in the body, particularly in the scalp. 
       
    • Hair Follicle Protection: With reduced DHT levels, hair follicles are less exposed to the negative effects of DHT, which can lead to hair miniaturization and loss. 
       
    • Hair Regrowth and Stabilization: In some cases, DHT blockers can help to stimulate hair regrowth and stabilize hair loss by creating a more favorable environment for hair growth. 
       
  • Examples of DHT Blockers:
    • Finasteride: A commonly prescribed medication for male pattern baldness that inhibits 5-alpha reductase. 
       
    • Dutasteride: Another 5-alpha reductase inhibitor that is also used for hair loss and prostate enlargement. 

Latanoprost

Latanoprost, originally used to treat glaucoma, has shown promise in promoting hair growth, particularly in alopecia and hypotrichosis, and is sometimes used off-label for hair loss. Studies indicate it can increase hair density and length, with some research suggesting it stimulates hair follicle activity and promotes regrowth.

Here’s a more detailed look at latanoprost for hair growth:

  • Mechanism:
    Latanoprost is a prostaglandin analog, and its mechanism of action in promoting hair growth is not fully understood, but it is believed to stimulate the anagen phase (the growth phase of hair) and increase the conversion of vellus hair (fine, short hair) to terminal hair (longer, coarser hair).

  • Clinical Studies:
    A 2023 systematic review and meta-analysis of 6 trials evaluated the efficacy and safety of topical prostaglandin analogs for hair loss, showing significant improvements in hair length and density compared to placebo with no notable difference in adverse effects between the treatment and control groups.

    A pilot study found that a 24-week therapy with latanoprost 0.1% solution led to increased hair density and pigmentation compared with placebo in male patients with androgenetic alopecia (AGA).

    Another study showed that latanoprost 0.005% topical solution significantly increased hair density and percentage of hair regrowth in scalp alopecia areata based on the SALT scoring system.

  • Side Effects:
    Potential side effects include scalp redness, irritation, itching, and discomfort.
    There’s also a risk of increased hair growth in nearby areas if latanoprost accidentally comes into contact with them (e.g., forehead, temples).

  • Combination Therapies:
    Latanoprost can be compounded with other hair loss treatments, such as minoxidil and finasteride, to potentially enhance effectiveness.

  • Bimatoprost vs. Latanoprost:
    Bimatoprost, another prostaglandin analog, has also shown promise in promoting hair growth, particularly in the treatment of alopecia and hypotrichosis.
    The choice between bimatoprost and latanoprost may depend on the characteristics of the preparation, planned storage, and other active ingredients present.
    Latanoprost has more demonstrated stability at acidic pH.

Benefits of Hair Restoration Medications

  • Stimulates hair growth: These medications can help to stimulate new hair growth in areas where hair has been lost or thinned.
  • Slows down hair loss: They can also help to slow down or stop the progression of hair loss.
  • Non-surgical: Avoids the risks and downtime associated with hair transplant surgery.
  • Convenient: Oral medications are taken daily, while topical medications are applied twice daily, making them easy to incorporate into your routine.

Uses for Medications for Hair Growth

  • Stimulating dormant hair follicles to promote regrowth

  • Slowing or preventing hair loss caused by genetics (male or female pattern baldness)

  • Increasing hair thickness and density for a fuller appearance

  • Blocking DHT (dihydrotestosterone), a hormone linked to hair loss

  • Improving scalp circulation to nourish hair follicles

  • Supporting post-hair transplant recovery for better graft survival

Vitamins and minerals:

  • Vitamin B1 (Thiamin)
    Vitamin B1 Helps Blood Flow to the Scalp & Hair Follicles. Whereas narrow blood vessels may restrict flow, causing the scalp to dry out, leading to dandruff and dry or brittle hair, vitamin B1 helps do the opposite: to ensure a healthy scalp, blood flow, and healthy, moisturized, and strong hair.

  • Vitamin B2 (Riboflavin) 
    Vitamin B2 is a powerful antioxidant that is integral to energy production. As a result, vitamin B2 can improve the health of your scalp, contributing to healthy hair growth. It would help if you also had vitamin B2 to digest vitamin B6. A deficiency in one typically leads to a deficiency in the other.

  • Vitamin B6 (Pyridoxine HCl)
    Vitamin B6 supports healthy hair growth by aiding in protein metabolism and the production of keratin, a key structural component of hair. It also helps regulate hormones that can contribute to hair thinning when imbalanced.

  • Vitamin B5 (Panthotenic acid) 
    Vitamin B5 helps strengthen hair follicles and improves moisture retention, leading to shinier, more resilient strands. It also supports the adrenal glands, which play a role in managing stress-related hair loss.

  • Vitamin B9 (Folic acid) 
    Folic acid promotes healthy cell division, which is essential for the growth of hair follicles and new hair strands. It also contributes to improved blood circulation in the scalp, enhancing nutrient delivery to the roots.

  • Vitamin B12 (Methylcobalamine) 
    Vitamin B12 plays a crucial role in red blood cell formation, ensuring that hair follicles receive adequate oxygen and nutrients. A deficiency in B12 can lead to hair thinning or slower growth over time.

  • Zinc Gluconate:
    Zinc gluconate supports hair tissue growth and repair, and helps maintain the oil glands around the follicles. It also plays a role in preventing hair loss by balancing hormone levels and reducing inflammation.

Benefits of various vitamins and minerals for Hair

As Vitamin B1 is important for the metabolism of macro and micronutrients in the body, the nutrient plays an important role in boosting overall health, including hair health. The key thiamine benefits for hair are:

  • Improves Scalp Health:
    Thiamine reduces blood vessel constriction. The dilated blood vessels carry more oxygen and nutrition to the hair follicles. Well-nourished hair follicles support better hair growth with healthier hair strands.

  • Reduces Hair Fall:
    Studies show that Vitamin B deficiency is directly linked to increased hair fall. Its role in the body’s energy metabolism processes converts nutrients into energy that is used by the hair follicles. Therefore, restoring the levels of the vitamin in the body is a potent remedy to reduce hair fall.

  • Strengthens Brittle Hair:
    Brittle hair is a result of increased oxidative stress. Vitamin B is a potent antioxidant that fights the free radicals in the body. It fights oxidative damage and nourishes the hair from within, preventing it from split ends and brittleness.

  • Adds Hair Luster:
    Thiamine for hair is an overall tonic for hair growth. It ensures hair that is healthier from the roots to the ends. This adds strength, volume, and luster to the hair, making it more manageable and glossy.

FAQs

How long will it take to see results?

It may take several months to see noticeable results from hair restoration medications. It’s important to be patient and consistent with your treatment.

Possible side effects vary depending on the medication. Common side effects include scalp irritation, unwanted hair growth in other areas, and sexual side effects (with finasteride and dutasteride).

The cost varies depending on the medication and whether you have insurance coverage.

The most commonly used and effective medications are Minoxidil (Rogaine), which stimulates hair follicles to promote growth, and Finasteride (Propecia), which blocks DHT, a hormone linked to hair loss. Some individuals may benefit from a combination of treatments for optimal results.

Yes, medications can be combined with PRP therapy, microneedling, laser therapy, and hair transplants to enhance results and improve overall hair density and strength.

Contact Medrein Health & Aesthetics in Southlake, TX to schedule a consultation. Our healthcare providers will assess your hair loss and recommend the best treatment options for you.

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