How far is Medrein Health from Irving?

Medrein Health & Aesthetics is located approximately 15 miles from Irving, typically a 20-25 minutes drive depending on traffic. We're conveniently located at 420 N Kimball Ave, Southlake, TX 76092.

Do you see many patients from Irving?

Yes! We serve many patients from Irving and throughout the DFW metroplex. Irving residents appreciate our convenient location and choose to make the short drive for Dr. Mikki's expertise and our comprehensive services.

What services are most popular with Irving patients?

Irving patients commonly seek Botox, dermal fillers, laser treatments, medical weight loss programs, and comprehensive aesthetic consultations. We tailor all treatments to individual goals and needs.

Retatrutide Peptide Therapy for Weight Loss in Southlake, TX

Southlake & DFW Area

Retatrutide represents the next evolution in medical weight loss—a triple-agonist peptide that targets three metabolic pathways simultaneously for potentially superior results compared to existing GLP-1 medications. At Medrein Health and Aesthetics in Southlake, TX, Dr. Haritha Mikkilineni (Dr. Mikki) offers this advanced therapy as part of comprehensive, physician-supervised weight management programs.

What Is Retatrutide?

Retatrutide is an investigational peptide that activates three key receptors involved in metabolism and appetite regulation: GLP-1 (glucagon-like peptide-1) which reduces appetite and slows gastric emptying, GIP (glucose-dependent insulinotropic polypeptide) which enhances insulin response and may improve fat metabolism, and Glucagon receptor which increases energy expenditure and promotes fat breakdown.

This triple-action mechanism distinguishes Retatrutide from semaglutide (which targets only GLP-1) and tirzepatide (which targets GLP-1 and GIP). Early clinical trials have shown remarkable weight loss results, with some participants losing up to 24% of their body weight.

Retatrutide vs. Tirzepatide vs. Semaglutide

If you’ve tried semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound) with limited success—or you’re looking for more significant results—Retatrutide may offer advantages. The addition of glucagon receptor activation increases your metabolic rate and promotes more aggressive fat burning, potentially leading to greater weight loss than dual-agonist medications.

Patients who have plateaued on other GLP-1 medications often find renewed progress with Retatrutide. Dr. Mikki evaluates your previous treatment history and current health status to determine if transitioning to this advanced peptide makes sense for your goals.

Benefits Beyond Weight Loss

While dramatic weight reduction is the primary benefit, Retatrutide offers additional metabolic advantages including improved blood sugar control and insulin sensitivity, reduced cardiovascular risk factors, potential improvements in fatty liver disease, decreased inflammation markers, and enhanced metabolic flexibility.

These benefits make Retatrutide particularly valuable for patients with metabolic syndrome, prediabetes, or those concerned about the long-term health consequences of excess weight.

Is Retatrutide Right for You?

Dr. Mikki considers Retatrutide for adults with a BMI of 30 or higher, individuals with BMI 27+ who have weight-related health conditions, patients who haven’t achieved goals with semaglutide or tirzepatide, and those seeking significant, sustainable weight loss under medical supervision.

Your consultation includes comprehensive metabolic assessment, review of previous weight loss attempts, and discussion of realistic expectations. Dr. Mikki’s extensive medical background ensures safe prescribing and monitoring throughout your treatment.

Your Medical Weight Loss Journey at Medrein Health

Retatrutide is administered as a weekly subcutaneous injection, with doses gradually titrated based on your response and tolerance. Dr. Mikki monitors your progress through regular check-ins, adjusting your protocol as needed to optimize results while minimizing side effects.

For comprehensive metabolic optimization, Retatrutide can be combined with NAD+ therapy for cellular energy support, hormone optimization to address metabolic contributors to weight gain, and body contouring treatments as you achieve your goals.

Medrein Health also offers tirzepatide and semaglutide for patients who may be better suited to these established medications.

FAQs

What is Retatrutide and how does it work?

Retatrutide is a triple-agonist peptide that activates three key receptors: GLP-1, GIP, and glucagon. This multi-target approach enhances appetite control, increases metabolic rate, and promotes fat burning more effectively than single or dual-agonist medications like semaglutide or tirzepatide.

How does Retatrutide compare to Tirzepatide and Semaglutide?

While semaglutide targets GLP-1 and tirzepatide targets GLP-1 plus GIP, Retatrutide adds glucagon receptor activation. Clinical trials have shown Retatrutide may produce greater weight loss results, with some participants losing up to 24% of body weight in studies.

Who is a candidate for Retatrutide therapy?

Ideal candidates include adults with a BMI of 30 or higher, or those with a BMI of 27+ with weight-related health conditions. Patients who have plateaued on other GLP-1 medications may also benefit. Dr. Mikki evaluates each patient individually.

What results can I expect from Retatrutide?

Clinical data shows significant weight loss potential with Retatrutide. Most patients experience reduced appetite, improved blood sugar control, and steady weight reduction. Individual results depend on dosing, lifestyle factors, and treatment duration.

What are the side effects of Retatrutide?

Common side effects are similar to other GLP-1 medications and may include mild nausea, decreased appetite, and digestive changes. These typically diminish as your body adjusts. Dr. Mikki monitors all patients closely and adjusts protocols as needed.

Ready to explore next-generation weight loss?

Schedule your Retatrutide consultation with Dr. Mikki at Medrein Health and Aesthetics in Southlake, TX. Call 214-702-5225 or book online today.