Medically reviewed by
Dr. Haritha Mikkilineni, MD
A Physician-Led Med Spa Serving Grapevine
One board-certified physician, one address, and a treatment plan set at your consultation.
- Google 4.8★
- Yelp 5.0★
Living and working in Grapevine
Grapevine's identity sits on Main Street. The Historic Main Street District, in ZIP code 76051, holds nine winery tasting rooms, the Vintage Railroad depot, and the Glockenspiel Clock Tower along a walkable strip of restored storefronts, with the Grapevine Main entertainment district at its gateway. It is built for an evening out on foot, not a quick errand.
The other side of town runs on a different clock. Gaylord Texan Resort & Convention Center, with more than 1,800 guest rooms on Lake Grapevine, hosts weddings and conferences, and the city's southern edge holds the bulk of DFW International Airport, including all six of its passenger terminals. Grapevine Mills, the outlet and entertainment mall, sits near that same airport edge. Between the lake, the mall, and the runways, a lot of life here runs on event calendars and flight schedules, not a fixed nine-to-five.
Residentially, it is a city of roughly 50,000 people spread across about 32 square miles: blocks around Main Street, newer streets closer to the lake, and neighborhoods that back up to the airport's buffer land. Grapevine-Colleyville ISD covers the schools on this side of town.
From Main Street, the Southlake clinic is a straight run west on SH-114, about 8 minutes and under 3 miles to N Kimball Ave, just south of the highway. Coming from the Gaylord Texan side instead adds a few minutes on Dove Road, closer to 11, and DFW Airport itself sits about the same distance down the highway in the other direction. Medrein Health & Aesthetics is open Mon–Fri 10:00 AM – 5:30 PM at 420 N Kimball Ave, Suite 140, Southlake, TX 76092.
Serving Grapevine from Southlake, TX
What fits life in Grapevine
Grapevine's calendar runs on weddings, wine weekends, and flight schedules, so these three are picked to fit a fixed date or a short window, not an open week.
Dermal Fillers
Between the Gaylord Texan Resort and the venues around Main Street, Grapevine hosts a lot of weddings and events, each tied to a fixed date. Dermal fillers are a common choice for brides, wedding guests, and bridal-party bookings who want results ready for that date, not on an open schedule. Dr. Mikki plans volume and placement at your consultation, with enough lead time for any swelling to settle beforehand. The same timeline works whether the event is at Gaylord Texan, a backyard reception, or a Main Street venue.
Candidacy is confirmed at your consultation.
HydraFacial
For a Saturday wine-tasting walk down Main Street or a weekday flight out of DFW, a HydraFacial fits around either schedule: cleanse, extract, and hydrate in one session with no downtime after. It is a popular choice for frequent travelers in the area who want a refresh between trips, and for anyone heading to Main Street or Gaylord Texan without time to recover from a more involved treatment.
Candidacy is confirmed at your consultation.
Dermaplaning
Dermaplaning clears surface buildup and peach fuzz in one pass, with no downtime and no appointment to plan around afterward. It suits days built around short windows between flights, work trips through DFW, or an evening on Main Street. It is also a common pairing just before other facial treatments on the same visit.
Candidacy is confirmed at your consultation.
One physician, one clinic in Southlake
Medrein has a single address, and the physician who consults with you is the one who treats you. The full story is on our about page and the Southlake med spa page.
-
A board-certified MD in the room. Dr. Haritha Mikkilineni, MD, holds every consultation and performs most procedures herself.
-
Named device platforms. Genuine Fotona, Sciton and Pico systems, each named on its treatment page.
-
Aesthetics and wellness together. Skin, injectables, weight loss, hormones and peptides in one plan.
-
A plan written at consultation. Including an honest answer when a treatment is not worth doing.
-
Medical-grade safety. FDA-cleared devices and a contraindication review before anything is booked.
-
Follow-up built in. Written aftercare, a check on how you responded, and doses adjusted at review.
Every treatment the clinic offers is open to you: aesthetics, laser and energy work, and longevity and wellness care. Candidacy is confirmed at consultation, and individual results vary.
Notes from patients who make the Main Street drive
These reflect common patient sentiment rather than verbatim quotes, and individual results vary.
Dr. Mikki took the time to walk me through my options and was honest about what she thought I did and didn't need. She created a plan that felt right for me and performed the treatment herself. That level of honesty is why I still make the drive.
A board-certified doctor chose my laser settings and then ran the treatment herself, on a platform she named up front. Worth the few minutes up the road.
Nearby areas from the same Southlake clinic
Serving Colleyville
Colleyville is the next city over, connected by Hall Johnson Road and the same Grapevine-Colleyville ISD; the same Southlake clinic and physician see patients from either side.
Serving Flower Mound
Flower Mound sits on the far side of Grapevine Lake, reached by looping around the water on FM 2499 to get to the same Southlake clinic.
Service-area maps show each community and the Southlake clinic. Map data © OpenStreetMap contributors.
Questions from Main Street to Southlake
How far is the Southlake clinic from Main Street?
About 8 minutes and under 3 miles. The route runs west on SH-114 past William D. Tate Avenue, then onto TX-114 Business/E Southlake Boulevard to N Kimball Ave, where the clinic sits just south of the highway.
I’m flying out of DFW the same day. Is there enough time for a quick visit?
Yes, there’s enough time for a quick visit. The airport’s terminals sit inside Grapevine’s own city limits, and the clinic is about 8 minutes further down SH-114 from there. A HydraFacial or a dermaplaning session, both with no downtime, fit before a flight with room to spare.
Does the drive change if I’m coming from the Gaylord Texan side instead of Main Street?
Yes, slightly: from that side, the route runs down N Kimball Ave and Dove Road instead of SH-114, for a total closer to 11 minutes instead of 8, since Dove Road takes a different line to the highway.
I’m getting ready for an event at Gaylord Texan. Should I book a consultation first?
Yes, book a consultation first. Every treatment starts with one regardless of your event date. Dr. Mikki confirms candidacy and sets timing at that visit, including how much lead time a treatment like dermal filler needs before the date, so there is no guessing on your end.
If I book a HydraFacial or dermaplaning before a night out on Main Street, is there anything to avoid right after?
No, both have no downtime, so heading straight to dinner or a tasting room afterward is fine. You get written aftercare for whatever you book, with anything specific to watch for spelled out at that visit, not left for you to guess.
How do I book from Grapevine?
Book online through our scheduling partner or call (214) 702-5225. No referral is required.
Book your consultation from Grapevine
Dr. Mikki maps your goals, confirms candidacy, and sets timing around your date. About 8 minutes west on SH-114 to Southlake.